Aziz Ganiev gave the lead for the Dragons in the 25th minute of the game as the hosts went to the break with a 1-0 advantage.
Bobir Abdikholikov doubled the scoring for FC Nasaf 7 minutes into the second period before Sanjar Tursunov halved the deficit for the visitors just 1 minute to complete.
Humoyun Murtazoev returned the two-goal lead for Ruzikul Berdiev’s side in the second period stoppage time.
Superleague Matchday 16
Stadium: "Central" stadium in Karshi
Referee: Zokir Qodirov