Ferghana side took the lead through Otabek Zokirov as he converted a goal from a 12-yard mark in the 31st minute.
15 minutes into the second period, Jasur Kholturaev canceled out FC Neftchi's opener before Shokir Yuldoshev put the hosts in front as they came back from behind at the Guzor Stadium.
Uzbekistan Cup Second stage
Stadium: "Guzar" stadium. Guzar
Referee: Rustam Lutfulin