As has been the case throughout the tournament, there was high drama in the Round of 16 as the eight teams gave it their all in a bid to advance to the quarter-finals, with Monday's draw in Doha pitting Al Nassr against Al Ahli Saudi FC in an all-Saudi Arabia last eight tie with Islamic Republic of Iran's Persepolis to face Uzbekistan's Pakhtakor on Wednesday.
Steely determination, late drama and a penalty shootout decided the Round of 16 as the West Zone inched closer to determining its representative for the 2020 AFC Champions League final on December 19.
Azizjon Ganiev gave Shabab Al Ahli Dubai the lead on Saturday but it was not to be as Al Ahli Saudi FC won the penalty shootout to advance to the quarter-finals.
Omar Al Soma pulled Al Ahli Saudi FC back into the tie against Shabab Al Ahli Dubai, with the Saudi side eventually winning the penalty shootout.
Ali Karimi gave Esteghlal the lead but it was not to be as Pakhtakor fought back to win 2-1 on Saturday.
Dragan Ceran drew Pakhtakor level as the Uzbekistan side saw off the challenge of Esteghlal FC to advance to the quarter-finals of the AFC Champions League for the first time since 2009.
Eren Derdiyok scored in the 47th minute against Esteghlal on Saturday to seal Pakhtakor their first AFC Champions League quarter-final berth since 2009.
Isa Al Kasir rose high to head home as Persepolis FC defeated Al Sadd SC on Sunday.
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