Andrey Sidorov's header broke the deadlock after a 68-minute goalless period at the Yoshlik Stadium.
However, FC Kizilkum levelled the scoring as Alisher Sanoev found back of the net entering the box just two minutes later.
In the injury minutes, Askar Najafaliev pointed to the spot for the hosts, but Artur Geworkian failed to score a goal from a penalty kick.
Superleague Matchday 31
Stadium: "Yoshlik" stadium, 4587 spectators
Referee: Asker Najafaliev