Karshi side went to the break with a 1-0 lead after Marko Stanoevich broke the 21-minute deadlock at the Karshi Central Stadium.
Sardor Rakhmonov equalised the scoring just few seconds into the second half, but Oybek Bozorov returned the advantage to FC Nasaf in the 60th minute of the game.
Superleague Matchday 20
Stadium: "Central" stadium in Karshi, 998 spectators
Referee: Rahim Karimov