Top two sides will qualify for the quarterfinals as the pairings will be allocated in another draw after the group stage matches.
The defending champions FC Pakhtakor will have FC Bunyodkor, FC Kokand, FC Oktepa for company in Group D.
FC AGMK, the underdog champions in 2018, were drawn in an enticing Group A with FC Navbahor, FC Andijan and FC Metallurg.
FC Nasaf, FC Surkhon, FC Kizilkum and FC Mashal will tussle for the two quarter-final slots from Group B.
Three-time winners FC Lokomotiv will have hosts FC Bukhara, FC Shurtan and FC Sogdiana for a company in Group C.
2020 Uzbekistan Cup | Group Stage